Service platform

Service Platform

Small molecule drug CDMO service

Small Molecule Drugs CDMO Service


Jiuzhou Pharmaceutical provides pre-clinical CMC (CHEMICAL MANUFACTURING AND CONTROL) to customers worldwide,Chemical composition production and control),Clinical stage I, II, III,One-stop service for the whole industry chain from NDA (NEW DRUG APPLICATION) to global listing。

Small molecule drug CDMO service

Efficient and professional global small molecule API R&D team

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1000 +

Scientific researcher

(This data is up to half year 2023)

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900 +

New drug program

Scientific researcher

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29

Commercial project

Scientific researcher

Meet different conditions of pilot production capacity

cGMP KG laboratory

Number of reactors: 43

Reactor size: 20-750L

Stainless steel pressure reactor 19L

Pressure reactor: 0.5 - 2.0L

Stainless steel basket centrifuge

Ozone generator

cGMP Laboratory (Taizhou)

cGMP Laboratory (Taizhou)

Number of reactors :43
Reactor size: 20-750L 
Stainless steel pressure reactor :19L 
Pressure reactor :0.5 - 2.0L 
Stainless steel basket centrifuge    
Ozone generator 

cGMP Laboratories (USA)

cGMP Laboratories (USA)

Reactor size: 72-750L
Stainless steel pressure reactor :19L
Pressure reactor :0.5-2.0L
Stainless steel basket centrifuge
Ozone generator
Kg cGMP batch production

cGMP Laboratory (Taizhou)

cGMP Laboratory (Taizhou)

Number of reactors :43
Reactor size: 20-750L 
Stainless steel pressure reactor :19L 
Pressure reactor :0.5 - 2.0L 
Stainless steel basket centrifuge    
Ozone generator 

cGMP Laboratories (USA)

cGMP Laboratories (USA)

Reactor size: 72-750L
Stainless steel pressure reactor :19L
Pressure reactor :0.5-2.0L
Stainless steel basket centrifuge
Ozone generator
Kg cGMP batch production

Pilot Workshop (Taizhou)

Pilot Workshop (Taizhou)

Production workshop: 8 
Number of reactors :208 
Reactor size: 30-2,000L   
Maximum reaction temperature :250 ℃  
The lowest reaction temperature: -80 ℃ 

Pilot Workshop (Hangzhou)

Pilot Workshop (Hangzhou)

Production workshop: 8 
Number of reactors :208 
Reactor size: 30-2,000L   
Maximum reaction temperature :250 ℃  
The lowest reaction temperature: -80 ℃ 

Pilot plant

Production workshop: 8

Number of reactors: 208

Reactor size: 30-2,000L

Maximum reaction temperature: 250 ℃

The lowest reaction temperature: -80 ℃

Commercial production capacity of apis to meet different needs

With more than 50 production lines, including large dedicated workshops, multi-functional workshops and pilot workshops, to meet the production needs of different scales from kg to ton

Equipped with cGMP compliant advanced API production equipment, can undertake a variety of reaction types, including high pressure dehydrogenation reaction, cryogenic reaction。High activity production facilities have been established, including 2 OEB-5 production lines and 6 OEB-4 production lines

The production base is equipped with automatic facilities and equipment such as DCS system to realize the automatic control of operation modules such as temperature control and inert gas protection material transmission. At the same time, SIS system is configured for dangerous processes to achieve stable and safe intelligent manufacturing

Productive capacity

Specific reactivity

Strong hydrogenation reaction ability

▪ Hydrogenation reactor volume: 100L-10,000L

Ultra-low temperature cryogenic response capacity

▪ Minimum temperature: -80°C
▪ Cryogenic reactor volume: 200L-2,000L

 

High temperature reactivity

▪ Max. 350°C(high temperature reaction) 

Diversified advanced technology

▪ Safe Grignard reaction
▪ Multiple enzymes catalyze the reaction
▪ Industrialization of continuous production capacity (G → 100 kg → 100 ton)