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Preparation technology for external use
Topical Formulation Technology
Semi-solid preparation for external use is generally divided into locally acting drugs and drugs absorbed into the blood circulation through the skin to achieve systemic effects according to the classification of effect, the dosage forms mainly include ointment, cream, gel, suppository and so on。
The development and improvement of topical preparations is to optimize the dosage form and administration route of marketed drugs with known active ingredients to better meet clinical needs。Due to the complex structure of external dosage forms, the physical properties of the preparation are affected by many factors, such as particle size, interphase tension, drug distribution coefficient between phases and product rheology。
Representative products: Creborol ointment, Voltaline ointment, progesterone vaginal sustained release gel, progesterone supt, etc。
